ESSENTIALS I COLLECTION

$400.00

$288.00

ESSENTIALS I COLLECTION

Name: ESSENTIALS I COLLECTION
Brand: Alchemy 21/12
Price: 288.00 USD
Availability: InStock

The Daily Foundation

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$400.00

$288.00

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A complete five-step ritual for cleansing, refined resurfacing, layered hydration, and barrier-supportive moisture.

Barrier Cleanser
Recover-Me EGCG + PAD Toner
Enzyme + PHA Resurfacing Polish
Crystal PDRN Glass Serum
Recover-Me Barrier Cream

Essentials I brings together the foundational steps of the Alchemy Ritual in one complete daily system.

Begin with Barrier Cleanser to lift away buildup without leaving skin feeling stripped. Follow with Recover-Me EGCG + PAD Toner to replenish lightweight hydration and prepare the skin for treatment. Enzyme + PHA Resurfacing Polish provides refined, non-abrasive renewal, while Crystal PDRN Glass Serum layers multi-level hydration with PDRN, snow mushroom, and skin-identical moisture support. Recover-Me Barrier Cream completes the ritual with biomimetic moisture designed to reinforce softness, resilience, and comfort.

Used together, the five formulas help skin look smoother, calmer, more luminous, and beautifully supported over time.

Quantity

WHAT IT DOES

Each product performs a distinct role within the ritual, allowing the skin to receive hydration, renewal, and barrier support in intentional layers rather than through one overloaded formula.

The system combines gentle cleansing, controlled resurfacing, water-binding hydration, PDRN-powered treatment, and biomimetic moisture to create the conditions for healthier-looking, more resilient skin.

WHY IT WORKS

CLEANS + PREPARES
Removes buildup while preserving skin comfort.

REFINES
Gently sweeps away dull surface buildup without harsh abrasion.

HYDRATES
Layers humectants, PDRN, and skin-identical moisture support.

STRENGTHENS
Replenishes the barrier with biomimetic and restorative ingredients.

HOW TO USE

Daily (Morning + Evening):

1. Cleanse
Massage Barrier Cleanser onto damp skin and rinse thoroughly.

2. Hydrate
Mist Recover-Me Hydrating Toner over clean skin or press in with the hands.

3. Treat
Apply Crystal PDRN Glass Serum and allow it to absorb.

4. Seal
Finish with Recover-Me Barrier Cream.

One to three times weekly:

Use Enzyme + PHA Resurfacing Polish after cleansing and before toner. Apply a thin, even layer, allow it to work as directed, then rinse thoroughly before continuing the ritual.

Ritual order

Cleanse → Polish → Hydrate → Treat → Seal

Pairs well with

AHK PEPTIDE HAIR & SCALP SERUM

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GHK NIGHT CREAM

$198.00

$148.00

RECOVER-ME 3S CORRECTV COMPLEX

$128.00

$96.00

THE RITUAL BEGINS

For Skin Experiencing

A complete daily foundation for skin that needs gentle cleansing, replenished hydration, visible calm, and lasting barrier support.

Dehydration

Dullness

Sensitivity

Uneven Texture

Compromised Barrier

Loss of Comfort

Hydrate

206.55%

More of a key water-holding protein

Measured: filaggrin expression

Red Ginseng PDRN

What it means for your skin

Help skin hold onto the water you give it.

Red ginseng PDRN increased two proteins involved in hydration retention and barrier cohesion in ex-vivo skin. The result is a hydration story that goes deeper than temporary surface moisture.

206.55% More of a key water-holding protein Filaggrin · ex vivo

154.47% More of a key barrier-sealing protein Claudin-1 · ex vivo

See what was measured

In supplier ex-vivo testing, RG PDRN 1000 at the tested 1% concentration increased filaggrin expression by 206.55% and claudin-1 expression by 154.47% versus untreated tissue.

Filaggrin contributes to formation of the outer skin layer and natural moisturizing factors. Claudin-1 helps maintain tight junctions between epidermal cells.

Source: CoSeedBioPharm RG PDRN 1000 efficacy dossier, 2026.

Calm

95%

Visible redness disappeared at clinical follow-up

Clinically assessed facial erythema

PAD · PT-8 · EGCG

What it means for your skin

Redness is the visible signal. These actives address the response behind it.

PAD targets visible erythema and inflammatory skin stress. PT-8 helps quiet an irritation-associated heat response. EGCG supports antioxidant defense against stress pathways that can keep skin looking red and reactive.

95% Facial erythema disappeared at follow-up PAD formula · human study

78% Lower irritation-associated heat response PT-8 formula · human challenge

51% Lower expression of a stress-response marker EGCG formula · human tissue

See what was measured

PAD: In a randomized, double-blind, placebo-controlled pilot study, 42 participants used either a cream containing 5% potassium azeloyl diglycinate plus 1% hydroxypropyl chitosan or placebo twice daily for four weeks. Clinical inspection reported facial erythema disappearing in 95% of treated participants by day 42.

PT-8: In a 13-person SDS challenge, a formula containing Palmitoyl Tripeptide-8 reduced the irritation-associated skin-temperature rise by 78% when applied after the challenge.

EGCG: In a four-person split-face study, a 2.5% EGCG cream reduced HIF-1α-positive epidermal staining from 28.4% to 13.8%, a 51.4% relative reduction, after six weeks.

Published studies used different finished formulas, concentrations, and delivery systems than Essentials I.

PAD study PT-8 study EGCG study

Strengthen

126.65%

Restoration of a UV-depleted water-holding protein

Measured: filaggrin expression after UV stress

Red Ginseng PDRN

What it means for your skin

Strength measured after stress, not only before it.

In ingredient-level testing, red ginseng PDRN helped restore proteins associated with hydration and barrier cohesion after UV challenge, while also improving survival among UV-stressed fibroblasts.

126.65% Higher expression of a UV-depleted water-holding protein Filaggrin · in vitro

98.15% Higher expression of a UV-depleted barrier-sealing protein Claudin-1 · in vitro

33.90% Restoration of UV-reduced fibroblast survival Fibroblast viability · in vitro

See what was measured

In supplier laboratory testing at the tested 0.3% concentration, RG PDRN 1000 increased UV-reduced filaggrin expression by 126.65% and UV-reduced claudin-1 expression by 98.15%.

In a separate UV challenge, the supplier reported 33.90% restoration of UV-reduced fibroblast survival at 0.3%.

Source: CoSeedBioPharm RG PDRN 1000 efficacy dossier, 2026.

Signal

147.29%

More collagen type I expression

Measured in ex-vivo skin

Red Ginseng PDRN · AH-8

What it means for your skin

Renewal signals that showed up in the data.

Red ginseng PDRN increased collagen type I expression, reduced expression of a collagen-breakdown enzyme, and increased the movement of skin-supporting fibroblasts. AH-8 adds published human anti-wrinkle evidence.

147.29% More collagen type I expression Red ginseng PDRN · ex vivo

58.75% Less expression of a collagen-breakdown enzyme MMP-1 · in vitro

28.54% Greater movement of skin-supporting cells Fibroblast migration · in vitro

48.9% Total anti-wrinkle efficacy AH-8 formula · human study

See what was measured

Red ginseng PDRN: Supplier testing reported a 147.29% increase in collagen type I expression in ex-vivo skin at the tested 1% concentration, 58.75% inhibition of MMP-1 expression at 0.3%, and a 28.54% increase in fibroblast migration at 0.3%.

AH-8: In a randomized, placebo-controlled study of 60 participants, topical Argireline / Acetyl Hexapeptide-8 produced 48.9% total anti-wrinkle efficacy after four weeks, compared with 0% for placebo.

The AH-8 study used a different finished formula and concentration than Crystal.

PDRN source: CoSeedBioPharm RG PDRN 1000 efficacy dossier, 2026. AH-8 study

Percentages shown reflect ingredient-level in-vitro, ex-vivo, supplier, or published human research conducted at the concentrations and in the vehicles identified in each study detail. Essentials I has not been clinically tested as a finished system, and these findings do not predict individual results.

ESSENTIALS I COLLECTION

The daily foundation.

Five essential steps designed to cleanse gently, resurface as needed, replenish hydration, support visible calm, and maintain a stronger, more comfortable barrier.

THE FOUNDATIONAL SYSTEM

Daily consistency, with targeted renewal built in.

Essentials I brings together five complementary formulas that support the core needs of healthy-looking skin without overcomplicating the routine.

Barrier Cleanser removes daily buildup without leaving skin tight or depleted.

Enzyme Polish provides periodic, gentle resurfacing to help lift dull buildup and refine the look of texture without relying on aggressive exfoliation.

Recover-Me EGCG + PAD Toner replenishes lightweight hydration while helping support visible calm, balance, and antioxidant defense.

Crystal PDRN Glass Serum delivers concentrated, moisture-binding hydration to smooth the look of dehydration and restore luminosity.

Barrier Cream seals in moisture with barrier-supportive lipids and replenishing actives to help preserve softness, comfort, and resilience.

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